Sunday, January 13, 2008


As the line between science fiction and reality becomes increasingly blurry, the Defense Advanced Research Projects Agency (DARPA) has always led the pack in terms of cool, weird, wacky and frightening innovations. This time Darpa-funded scientists have found a drug that eliminates sleepiness with a nasal spray of a key brain hormone. The spray has worked well in lab experiments, with no apparent side effects. The hope is that the hormone will serve as a promising sleep-replacement drug in humans.

The spray contains a naturally occurring brain hormone called orexin A. In tests, monkeys suffering from sleep deprivation were treated with the substance and were subsequently able to perform like well-rested monkeys on cognitive tests. Darpa is no doubt interested in the spray for it’s promise of keeping soldiers awake and alert during battle, but for those suffering from narcolepsy, the discovery may offers a potential treatment. Even those with less severe sleep disorders may be interested. According to the National Sleep Foundation, than 70 percent of Americans get less than the generally recommended eight hours of sleep per night and consequently suffer some type of sleep-deprivation symptoms. continue

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